Pac-12 picks against the spread: Can USC upset Oregon?

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November 14, 2015; Stanford, CA, USA; Oregon Ducks head coach Mark Helfrich celebrates after a play during the third quarter against the Stanford Cardinal at Stanford Stadium. The Ducks defeated the Cardinal 38-36. Mandatory Credit: Kyle Terada-USA TODAY Sports

  •  Date: Saturday November 21, 2015
  • Time: 3:30 PM Eastern
  • TV Channel: ESPN
  • Spread: Oregon -4.0
  • Over/Under Total: 71.5

This is definitely the best game of the weekend. There are still division hopes for both squads here, but USC is in the driver’s seat, only needing two more wins to fend off Utah and UCLA for the South. But the Oregon Ducks are playing like one of the best teams in the conference with four straight wins.

USC is also riding a four-game winning streak but they seem to have hit a wall after struggling with Arizona and Colorado in their last two games. Meanwhile, Oregon is coming off a big win over Stanford, and looks to show some fight to end their season.

It’s hard to imagine USC struggling three straight weeks, but I think that’s just the way their season is going to go down. Oregon is hot, and I don’t think the Trojans can come into Eugene and steal the win here, pushing Oregon to eight wins, something we didn’t think was possible five weeks ago.

Next: UCLA vs Utah