Previewing ACC football’s biggest games in Week 3

MORGANTOWN, WV - NOVEMBER 25: A student supporter of the West Virginia Mountaineers holds up a sign during the 2011 Backyard Brawl against the University of Pittsburgh Panthers on November 25, 2011 at Mountaineer Field in Morgantown, West Virginia. (Photo by Jared Wickerham/Getty Images)
MORGANTOWN, WV - NOVEMBER 25: A student supporter of the West Virginia Mountaineers holds up a sign during the 2011 Backyard Brawl against the University of Pittsburgh Panthers on November 25, 2011 at Mountaineer Field in Morgantown, West Virginia. (Photo by Jared Wickerham/Getty Images) /
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SYRACUSE, NEW YORK – SEPTEMBER 17: Jatius Geer #54 of the Syracuse Orange tackles Aidan O’Connell #16 of the Purdue Boilermakers during the fourth quarter at JMA Wireless Dome on September 17, 2022 in Syracuse, New York. (Photo by Bryan Bennett/Getty Images)
SYRACUSE, NEW YORK – SEPTEMBER 17: Jatius Geer #54 of the Syracuse Orange tackles Aidan O’Connell #16 of the Purdue Boilermakers during the fourth quarter at JMA Wireless Dome on September 17, 2022 in Syracuse, New York. (Photo by Bryan Bennett/Getty Images) /

Syracuse at Purdue

Purdue is sitting at 1-1 after being upset by Fresno State in week 1 and traveling to Lane Stadium and upsetting Virginia Tech in Week 2. Upsetting a  2-0 Syracuse team at home would be a great way to get back to a winning record. Last season, Syracuse beat Purdue 32-29 with seven seconds left in the game. Could we see a similar performance from both teams this weekend?

Who: Syracuse Orange (2-0) vs. Purdue Boilermakers (1-1)

Where: Ross-Ade Stadium, West Lafayette

When: 7:30 p.m., Saturday

TV: NBC

Line: Syracuse -2.5, o/u: 58.5

Prediction: Syracuse 28 – Purdue 23

Northwestern at #21 Duke

Nationally ranked in consecutive polls for the first time in eight years, Duke is no longer an underdog in games; in fact, they are favored this week by three scores. Northwestern’s program is in bad shape, interim coach David Braun lost 24-7 to Rutgers on Sept. 3 before beating UTEP this past week. The Blue Devils appear to have a clear advantage here. The only question is will Northwestern put up a fight or will they roll over?

Who: Northwestern Wildcats (1-1) vs. Duke Blue Devils (2-0)

Where: Wallace Wade Stadium, Durham

When: 3:30 p.m., Saturday

TV: ACC Network

Line: Duke -18.5, o/u: 46.5

Prediction: Duke 27 – Northwestern 13

Louisville vs. Indiana, in Indianapolis

Louisville football is off to its best start since 2017. Indiana is a  team that suffered a lopsided loss to Ohio State in week 1 before rebounding in week 2 against Indiana State. We may learn more about what to truly expect from both the Hoosiers and Cardinals for the rest of this season in this game.

Who: Louisville (2-0) vs. Indiana (1-1)

Where: Lucas Oil Stadium, Indianapolis, Ind.

When: Noon., Saturday

TV: Big Ten Network

Line: Louisville -9.5, o/u: 53.5

Prediction: Louisville 28 – Indiana 20