5 best college football bets in Week 1 of the 2021 season
4. Ole Miss (-10.5) vs. Louisville
The final game of the weekend will technically not even be on the weekend, but on Labor Day night as Ole Miss and Louisville head down to Atlanta for an interesting non-conference battle.
Whenever you match the ACC up with the SEC, you have to feel good about the latter’s chances, and I think this is a prime example of that.
Louisville is fresh off a disappointing 4-7 season under Scott Satterfield and the Cardinals are losing some key players like Javian Hawkins and Tutu Atwell, so things get that much more difficult for this offense which had plenty of question marks last season. Facing a team like Ole Miss without much of a defense should help, though.
I like Malik Cunningham, but I just don’t think he’s going to be able to keep pace with Matt Corral and that explosive Ole Miss offense.
Let’s face it, Lane Kiffin’s Rebels can put 14 points on the board before the opposing team even realizes the game has started. This will be a high-scoring affair for Ole Miss again but Louisville won’t keep up. I think Ole Miss will win by a couple of touchdowns, at least.