College Football Predictions: Picks for Top games of Week 4

We are back for College Football Predictions for Week 4 of the 2023 college football season which features some marquee matchups. 

Last week, the slate of college football games was fairly weak. There wasn’t even a top-25 matchup.

However, that’s not the case during Week 4 of the college football season. There are actually six top-25 matchups on the schedule and some other games that are intriguing too such as Florida State and Clemson.

Yet, we are going to stick with Top 25 matchups for our Week 4 College Football Predictions and my belief is that the Seminoles are going to beat the Tigers and further establish themselves as the team to beat in the ACC.

As far as the rest of the Week 4 games, here are our predictions for every top-25 game.

No. 19 Colorado at No. 10 Oregon (-21) (3:30 PM EST, ABC)

Colorado football has been taking the college football world by storm, but the Buffaloes will get their first real test this weekend against Oregon.

Nebraska and TCU are solid teams. Colorado State is 0-2 and was a play away from beating Colorado football last week.

Making matters worse for Colorado football is the fact that Travis Hunter is expected to miss the game due to an injury. He’s a dynamic two-way player and without him, it’s hard to see the defense doing enough to keep Colorado in the game.

Shedeur Sanders will play well and the Buffaloes will score some points, but Oregon finally ends the magic carpet ride.

Oregon 45, Colorado 31